Demonstrate a CoVid-19 testing rate of >10K tests/day using lab automation infrastructure.
The UK and Europe have a COVID crisis with cases increasing exponentially. At opencell we will deploy a testing system that uses liquid handling robots and molecular assays in order to increase testing capacity to >10K/day in 2 weeks.
We are facing a once in a century global pandemic. We have more world wars than pandemic case studies. We need to act quickly and efficiently to limit public harm. At the current exponential growth rate we will be seeing a daily increase of 1,000-10,000 infected people by the end of the month. The health service does not have the ability to complete that volume of testing. Testing is one way to reduce pressure on healthcare systems and to ensure that those infected undertake appropriate isolation procedures.
We will be creating this groundbreaking work
from OpenTrons. They describe an automated and scalable approach to massively increase sample testing by >10K/day per lab unit. By completing this rapid scale up we will be capable of guiding other lab facilities on adding this capability. The process and experiment
The process involves a core procedure: reverse transcription polymerase chain reaction (RT-qPCR), which acts to amplify a section of DNA (or RNA) molecules in a sample to a measurable level and complete a quantitative read out optically.